Somatropin: reviews, advice and benefits

Growth Hormone is to this day one of the best drugs for prolonged muscle building. So far it is the only drug that causes athletes to forget about the bad genetic inheritance. Injections of growth hormone – it is always some risk because some phenomena are not reversible. But, despite the risk of potential side effects, it is still one of the most popular drugs in athletes. Growth hormone is surrounded by an aura of mystery in its application. Some call it a miracle means that in a short time gives a huge increase in strength and muscle mass.

Others consider it completely useless in achieving sports results and explain it by the fact that the drug stimulates the growth of only “dwarfs”: lagging behind in physical development of children. Some people think that growth hormones in adults cause a terrible bone deformities in the form of the Habsburg jaw and tremendous growth. There is also a complete mess: how to use growth hormones and in what dosage? Disagreements over hormones are so complex that the reader must have some initial basic information to understand the problem. Details

 

Growth Hormone – a polypeptide consisting of 191 amino acids. It is produced by the human pituitary gland and is released when the relevant stimuli (eg training, sleep, stress, low blood sugar). And here it is important to understand that the liberated human growth hormone does not have any direct influence itself on the body, but only stimulates the liver and subsequent release into the blood, and insulin-like growth factors, somatomedins. They have different effects on the body. The only problem is that the liver can develop a limited number of these substances, so that the effect of these substances on the body is limited. If hormone injections administered externally, they only stimulate the liver to produce and release these substances in the blood and does not have, as stated above, the direct impact.

 

Until the mid-80s there was only active in the human form as an exogenous source of introduction into the body. It is extracted from the pituitary of dead that had to be extremely costly. When, in 1985. receiving human growth hormone became associated with the extremely rare disease Krayufalda Jakob disease (disease of the brain), which faded for a dementia and death, some, but not all manufacturers began to remove the drug from the proizvodstva.K Fortunately, science is not dozing, and has created a synthetic hormone growth which produce genetically engineered muscle from transformed cells. And seychast it is sold in many countries.

 

The use of three ways growth hormone affects the athlete in his achievements. In – First, the strongest growth hormone has an anabolic effect that promotes intense fusion protein that is expressed in muscle hypertrophy (increase in muscle cell size) and muscle hyperplasia (increase in number). hyperplasia effect is extremely interesting, because steroids do not give it. Perhaps this is the reason that STH is called the strongest anabolic hormone. Second, growth hormone exerts a strong influence on the process of burning fat. He strongly converts fat into energy, leading to the intensity of his disappearance, and it allows the athlete to use a greater number of calories. Third, it often goes unnoticed, so that STH strengthens the connective tissue, tendons, bones and cartilage, and this is probably one of the main reasons for the incredible growth of the forces, which is seen in some athletes. Bodybuilders and powerlifters report that STH protects, thanks to this quality, the athletes from injury, if at the same time taking steroids strength is growing rapidly.

 

But with all this, there are many athletes who took growth hormone and have not made any serious progress either. There are several explanations.

 

  1. Athlete regularly received insufficient amounts of the hormone, and, moreover, even for a short time. This is due to the fact that growth hormone – a very expensive drug, and for many in the necessary dose is unaffordable.

 

  1. When applying samatotropina increases body’s need for thyroid hormone, insulin, corticosteroids, gonadotropins, estrogens, as well as in androgen hormones. This is the reason that STH, taken as a single drug is not very effective. Wink its phenomenal growth hormone anabolic properties could only by sharing a steroids, thyroid hormone, and insulin (see. Insulin). Only in this case the liver and may generate the optimum amount of releasing insulinodobnyh somatomedins and growth factors. This anabolic formula can be further strengthened while taking substances with anti-catabolic properties, steroids and Clenbuterol. Only then comes a synergistic effect.

 

Yet once again return to the anabolic formula: growth hormone, insulin and L-T3. Most athletes have taken growth hormone in the preparation phase for the competition, ie, in the diet phase with a reduced number of calories. In this phase, the body reduces insulin and thyroid hormone L-T3. What is described above in paragraph 2, it is not the good condition for growth hormone. Those who combine Clenbuterol with STH should know that Clenbuterol (like Ephedrine) also reduces the own production of insulin and L-T3. We recognize that everything written here is rather difficult to understand, but it is necessary to know in order to maximize the effect of the use of growth hormone. We need to understand that growth hormone affects many hormones of the human body, and it makes it impossible to receive a simple scheme. Read more

 

Before we get to the very difficult subject of dosages and dosing regimens, the question arises: who will generally take growth hormones? Athletes almost all the power and speed sports, as evidenced by the quote: “Charlie Francis, the Canadian coach athlete Ben Johnson described how Ben and numerous athletes of the Olympic Games burst with growth hormones forward Francis has convincing arguments in favor of using athletics stars in the US. growth hormones. in short, not for the press, talk with a professional athlete bodybuilding named Gary Straydem, this incredibly massive athlete made clear that he is absolutely certain that growth hormone use almost all professional bodybuilding. he also added that he had nothing afraid of the doping control until they are tested for growth hormone. ” Professional footballer Pile Altsaf, who died of a brain tumor (author’s note: There is a version that perhaps he died from illness Jacob Creutzfeld), shortly before his death, admitted that taking hormones for 16 weeks, and said that 80% of US professional footballers also take growth hormone. “Many of the best fighters use growth hormones while paying thousands of dollars a year.” Due to the fact that the top athletes are often accused of taking growth hormones, it only fuels the interest in them in the non-professional circles. (Daniel Duchaine, A Guide to the underground steroids).

 

On the question of the proper dosage and duration of admission is rather difficult to answer. Because not conducted research on the effects of growth hormone on athletes, so you can only come from experience. With the growth of pituitary insufficiency caused by the absence or insufficient release of growth hormone by the pituitary gland, manufacturers are advised to: a weekly dose on average 0,6me / kg body weight. Those. 100kg first athlete would have to receive weekly injections 60me. This dose would be divided into three intramuscular injections of 20me vtechenie week. Another method of administration: subcutaneous injection, which must be administered daily, most frequently by 8me day. Top athletes, who have enough money to take daily 4-8me. Because STH has a half-life of less than one hour, many athletes divide their daily dose into 2-3 small subcutaneous injections of 2me.

The introduction of regular small doses is considered to be more effective. On the grounds there. As we know, STH stimulates the liver to produce and release somatomedins and insulin-like factors, which cause the body’s desired effects.

Because the liver can only produce a limited amount of these two substances, one can question the fact that for large injections of the liver is able to produce just the appropriate amount of somatomedin and insulin-like growth factors. Therefore, the liver responds better to frequent and small dosage. Who introduces a solution of growth hormone in the same place, notice that at the injection site occurs disappearance of adipose tissue.

Because the injection site should constantly change in order to avoid local lipotrofii (disappearance of adipose tissue). In just a few years after all it turned out that the effect of growth hormone is highly dependent on the dosage. This means that: a stocked money and take it properly, or you just throw your money away.

 

Effectively this 4-8me active dose per day. For comparison: the hypophysis of a healthy adult daily highlights 0.5-1.5me growth hormones. Course duration depends mostly on the financial capacity of the athlete. Based on experience, taking STH most often at least 6 weeks to several months.

 

Interestingly, the effects of the hormone does not decrease after a few weeks, so at the same dosage achieved permanent gains. Bodybuilders have a positive experience with growth hormone, report that the accumulated power and, especially, for the most part preserved muscles and after receiving the hormone. American physician Dr. William N. Taylor, confirms this in his book “Anabolic steroids and athletes”, where one can read: “Statements of the athletes that made the strength and weight after taking hormone stored, means an increase in the number of muscle cells (hyperplasia) in. nature, strength and muscles can grow further months later, as extended to the newly acquired muscle cells stimulated through training of muscle hypertrophy. ”

 

Undesirable effects of growth hormones, the so-called side effects, this is a very interesting topic that is causing heated debate. First of all, it should be noted that growth hormone causes the side effects are not similar to those observed when taking anabolic / androgenic steroids such as: reducing its own testosterone production, acne, hair loss, aggressiveness, elevated estrogen level, the phenomenon of virilization in women reinforced water and salt retention, etc.

 

There are two main problems: the first is the possible lack of sugar in the blood, and the second, the possible hypothyroidism, so it can not be used for diabetes and thyroid disorders. In very rare cases there is an antibody response after a few months after the initiation of growth hormone. But what about the horror stories about acromegaly, bone deformation increase in heart problems with various organs, gigantism, and early death? To answer this, it is necessary to distinguish between hormones intake in the pre – and poslepubertanny periods. Growth is possible if a person is in dopubertannom period. After the possible gains or bones due to hypersecretion of endogenous growth hormone or due to excessive inflow of exogenous growth hormone. People suffering from an endogenous hypersecretion in poslepubertanny period and finished with normal growth can occur acromegaly, ie bone becomes thicker, wider, but not longer. Sometimes there is some growth in the hands and feet, as well as an increase in facial features due to overgrowth of the lower jaw and nose. Heart muscle and kidneys can increase in volume and weight, which sometimes can lead to diabetes and heart disease that could theoretically lead to death. In this and speculating media, they represent extreme cases with sick people as examples and for scaring vdalblivanie athletes about what fate awaits them when taking growth hormones.

And yet it is so unlikely as the reality showed that these examples should not be taken into account. Among the many athletes taking growth hormone is relatively small two-meter Neanderthals with extended jaw and 56 feet in size. To avoid misunderstandings, we do not want to mitigate the side effects that occur in healthy adults, but we want to try to explain that acromegaly, diabetes, myocardial hypertrophy, high blood pressure, kidney and liver growth can theoretically occur when excessive debt and taking growth hormone. But in practice they are very rare.

More frequent problems with STH occur, judging from experience, when the athlete intends to inject insulin in addition and does not do it correctly. The substance somatropin is a dry powder prior to injection and should be divorced enclosed solution in a vial. The final solution should be administered immediately, or be stored in a refrigerator, but no more than 24 hours. It is advised to store in the refrigerator and unused medication. The biological activity of growth hormones when stored at room temperature (15-25S) for up to 4 weeks is not reduced, and should still prefer a cool place (2-8S).

 

{Mospagebreak “Oh, this is really a great product – the best way to build muscle is the only drug that makes you forget even about the bad genetic predisposition, as it helps to achieve a gain in muscle mass ANY HGH -.. Is the greatest risk, to which an athlete can go, because the side effects are irreversible and, in spite of it all, we love this drug. “, – he said about growth hormone in his book” Handbook of underground steroid “famous steroid guru Daniel Ducheyn.

 

Growth hormone – the most mysterious and controversial drug of those included in the arsenal of competing bodybuilders. Some believe that without it is impossible to make the championship form, others believe that he simply does not work, affecting only dwarfs, others told terrible things about the side effects caused by taking this medicine: grown to immense sizes jaws, noses and superciliary arches. And what is HGH really?

 

For a start – a little chemistry.

 

Growth Hormone – a polypeptide hormone consisting of 191 amino acids. It is produced by the human pituitary gland and is released when the relevant stimuli (eg, exercise, stress, sleep, irritation, low blood sugar). It is important to understand that produced as a result of this growth hormone does not have a direct impact on the body, but only stimulates the release of insulin into the blood growth factors and somatomedins, which some accepted and for the cause. The problem is that the liver is capable of producing only a limited number of these substances. And if hormones are injected from the outside, they only encourage the liver to produce and release these substances on the body without causing direct impact. Details

 

Until the mid-80s, there was only a natural human growth hormone, which was extracted from the pituitary of dead people. You understand that this procedure was incredibly expensive. When in 1985, receiving human growth hormone became associated with the extremely rare disease Krayufelda Jakob disease (disease of the brain), which entailed dementia and death, manufacturers began to remove the drug from the production. Today, almost do not sell human growth hormone injection (exception – Lithuanian “Growth Hormone”). Fortunately, science is not dozing, and invented a synthetic growth hormone, which is produced by genetic engineering and transformed muscle cells. Nowadays the artificial growth hormone sold in many countries under different trade names: “Humatrop”, “Norditropin”, “Somatosorm”, “Somatogen” etc.

 

How does the growth hormone?

 

In essence, it acts on the body in three ways. Firstly, it has a strong anabolic effect and enhances protein synthesis, resulting in muscle hypertrophy (increase in muscle cell size) and hyperplasia of muscle – to increase their number. The latter property growth hormone is unique in that anabolic steroids do not give a similar effect. Perhaps this is the reason that STH is called the strongest anabolic hormone. Secondly, the growth hormone exerts a strong influence on the burning of fat. He is intensely burns fat, it allows the athlete to consume more calories. Third, what is often overlooked, STH strengthens the connective tissue, tendons, bones and cartilage, which, apparently, is one of the main reasons for the incredible growth of the forces, which is seen in some athletes. Some bodybuilders and lifters are convinced that in this way the growth hormone protects them from injury, the likelihood of which increases dramatically the growth of parallel operating weights accompanying steroids. In addition, an increase in bone, cartilage, tendons and internal organs makes the athlete REALLY MASSIVE. And it is – not the mass, which “leaves”, as it happens when the user “gets off” on steroids.

 

However, some athletes tried growth hormone, we have not felt any positive changes. Why did this happen?

 

  1. Dosage was too low and / or it is used long enough. These concerns are understandable, since growth hormone is very expensive.

 

  1. Growth hormone used alone. The fact is that when taking the growth hormone rises sharply in the body’s need for thyroid hormone, insulin, corticosteroids, gonadotropins, estrogen, and steroids. Therefore, if the growth hormone is adopted alone, the effect is significantly reduced its effects. In fact, in order that the body was in an optimal anabolic state required three hormones: growth hormone, thyroid hormone A3 (Cytomel) and insulin. Only in this case, the liver is able to produce enough insulin somatomedins and growth factors. This anabolic state can be further enhanced by taking drugs that have pronounced anti-catabolic properties, such as clenbuterol. However, those who are going to combine the receiving growth hormone with clenbuterol or ephedrine, need to know that these drugs reduce the level of production of insulin hormone, and L3. A similar reduction occurs when the athlete sits on a rigid diet precontest.

 

  1. Instead of the growth hormone you slipped a fake or low-quality drug. Few people know how to actually should look like this drug, which is used by the dealers “black market”. At the pharmacy you it is unlikely to get it. At least, without a prescription. As for the poor quality of the preparation, it is known that growth hormone must be stored in a cool place, otherwise it starts to decompose. Therefore, if it is written on the bottle that it contains 4000 international units of growth hormone, there is no guarantee that they will not 3000 or 2000.

 

How to take growth hormone? In what dosage? How long?

 

These questions are difficult to answer, because there are no laboratory tests to this effect have been conducted. You can only rely on the experience of familiar with this piece of athletes. With the growth of pituitary insufficiency caused by the absence or low emission growth hormone by the pituitary gland, the manufacturers advise taking the drug weekly rate of 60 IU per 1 kg of body weight. Thus, an athlete weighing about 100 kg, must inject themselves about 6000 IU of HGH. At this dose of 6000 IU desirably divided into three doses of 2,000 IU. Another option – subcutaneous injection, which would have cost to enter each day, approximately 8,000 IU per day. The average dosage of top athletes is around 4000-8000 IU growth hormone daily. Because the half-life of growth hormone – less than an hour, many athletes prefer a daily dose divided into two parts, which are administered in the morning on an empty stomach and at night before bedtime – it is not considered optimal. Furthermore, since the liver is unable to produce insulin-like growth factors and somatodieny in limited quantities, it simply can not absorb large dosage of growth hormone from the outside, which again favors fractional receiving this drug.

 

Although some bodybuilders swear that they have achieved stunning results, taking all day and 2000 IU of growth hormone, you, if you are serious about working with this drug, it is necessary to stock up a decent amount of money to count still at 4,000 IU per day. Growth hormone should be taken either in a large amount, or not taken at all, because it simply does not work in a small dose, as described above.

 

As for the duration of the course, it should be at least six weeks and may last for several months. It is believed that the risk of side effects increases, if the duration of admission passes for six months. Interestingly, the effects of the hormone does not decrease after a few weeks after starting, so to increase the dosage, as is customary in the case of steroids, it makes no sense.

 

Positive properties of growth hormone consists in the fact that achieved with the help of strength and muscle volume, as a rule, do not decrease after the course. This is because, as already mentioned, with an increase in the number of muscle cells. Due to this, many athletes unable to progress for many months after the end of receiving growth hormone.

 

Another interesting feature of growth hormone is that frequent injections it in the same location may result in burn-in at this point fat. So it makes sense to introduce the drug in different body sites.

 

I would like to talk a bit about how growth hormone interacts with insulin. In fact, not too advanced athletes is not recommended to supplement the intake of growth hormone externally administered insulin – enough to fully eat every 3 hours. Thus you will maintain insulin levels are high enough. In addition, keep in mind that too much insulin makes you fat, because excess insulin activates certain enzymes which convert glucose into glycerol, and then in the triglycerol. On the other hand, too low a level of insulin in the blood, which is most likely to occur during the period of “drying” before the competition, dramatically reduces the effects of growth hormone on the body. The ideal option would be to find a doctor who would do you tests on blood and urine sugar levels and determine how much insulin you need.

 

Side effects.

 

Arising when receiving growth hormone side effects have nothing to do with adverse effects, which give steroids. I mean reduction of body testosterone, aggression, verilizatsiyu women, acne, water retention, increased estrogen levels, etc. The main problem – it is usually possible lack of sugar in the blood (the risk of diabetes) or possible hypothyroidism. Rarely occurring antibodies to growth hormone is not essential. As for the enhanced growth of individual organs and limbs, they, if they occur, in the pre-adolescent (that is, when a person has not yet formed) or poslepubertatnom, but only in people who suffer hypogonadal (hypogonadism). People suffering from an endogenous hypersecretion, acromegaly can occur poslepubertatny period. Bones become thicker, wider, but not longer. There is increased growth of hands and feet, as well as an increase in facial features due to overgrowth of the lower jaw and nose. Heart muscle and kidneys can increase in volume and weight. Often this ends with the onset of general weakness, diabetes, heart disease and premature death.

 

The media understandably inflate isolated cases to the level of universal tragedy, but it is recognized that the podium is not clogged with two-meter athletes with jaws like a Neanderthal. The above diseases are extremely rare, and in the case of very long-term use of growth hormone in very large doses. But such luxury can afford not everyone, given that the Lithuanian growth hormone production, the most widespread in the Russian market, worth approximately 5.5-8 dollars per vial containing 4000 IU of dry matter. The preparation is a light powder enclosed in a glass vial, to which was attached a vial with a solution (usually a solution of novocaine). The final solution should be administered immediately or stored in the refrigerator, but no more than 24 hours. It should be stored in the refrigerator and unused medication. Although the biological activity of growth hormone begins to decline only after four weeks of storage at room temperature, it is better to store it in the refrigerator.

 

Growth hormone is included in the number of doping, but almost “caught” on doping control, which makes it very popular among competing at the international level athletes. However, it may soon be supplanted by growth hormone open American and Australian scientists insulin-like growth factor, which allows the body to receive external getting more of the substance required to produce their own somatodienov and insulin-like growth factor. So the “chemical” bodybuilders is to pray for science, the possibility of which, it seems limitless!